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KC Brennan

Professor of Neurology and Adjunct Professor of Neurobiology

Optical and electrophysiological investigation of the basic mechanisms of migraine

Brennan KC

 

Molecular Biology Program

Education

B.A. Georgetown University

M.D. Columbia University College of Physicians and Surgeons
Medicine

Research

K.C. Brennan, MD, is a clinician scientist who specializes in the treatment of headache. disorders. His lab studies the basic mechanisms of migraine and post-traumatic headache.

Optical and electrophysiological investigation of the basic mechanisms of migraine

Dr. Brennan's laboratory studies derangements of brain excitability. A particular interest is cortical spreading depression (CSD), a wave of runaway excitation that is thought to be the basis of the migraine aura. CSD is also involved in traumatic brain injury, stroke, and epilepsy.

The lab uses a combination of techniques including optical intrinsic signal imaging and spectroscopy, voltage sensitive dye imaging, two-photon microscopy, and electrophysiology to study CSD and the disorders it affects.

References

Last Updated: 9/23/21