Curriculum
COVID-19 INFORMATION
CORE CURRICULUM OVERVIEW
- Designed to provide students with a solid background in key areas
- Designed to teach independent, critical thinking skills, and grant writing
- Designed to fulfill the NIH-mandated requirement for scientific ethics
- Curriculum Grid.pdf

CURRICULUM REQUIREMENTS
Biological Chemistry and Molecular Biology Program Students must maintain a GPA of at least 3.0, earn at least a B- in each of the core courses, and to remain in good standing and to be eligible for tuition waivers and stipend. Students must be registered full time for between 9-12 graduate credit hours per semester during Fall and Spring.
*DO NOT add or drop courses after the first day of the semester until you contact the Program Office for guidance
Fall Semester
The majority of Fall 2020 lecture and didadic courses will be online through Canvas with a combination of recorded and streamed lectures and IVC small group discussions through Zoom and other digital technology.
Lab rotations will be hybrid with limited in person interactions.
University Fall 2020 Class Schedule
ADVANCED STUDENT INFORMATION
Graduate Electives Fall 2020.pdf | Graduate Electives Fall 2019.pdf | Graduate Electives Fall 2018.pdf
BLCHM 6050 - Faculty Research Interest Seminars
Presentations on research interests of faculty in the Biological Chemistry Graduate Program.
Fall 2020 Schedule
0.5 Credit Hour, First Half Semester
Instructor: Michael Kay
BC Students should register for Section 001, Class 17126
MBIOL 6050 - Faculty Research Interest Seminars
Seminars on research interests of faculty in the Molecular Biology Graduate Program.
Fall 2020 Schedule
0.5 Credit Hour, First Half Semester
Instructor: Janis J Weis
MB Students should register for Section 001, Class 4777
BLCHM 6400 - Genetic Engineering
This course covers essential techniques used in genetic engineering. Assuming modest background in biology, the course introduces fundamental aspects of molecular biology including mechanisms for storage of information in DNA and transfer of this information to RNA and protein molecules. Manipulations of DNA molecules to rearrange or remodel genetic information (cloning) are described from both theoretical and practical viewpoints. Topics covered include the use of restriction endonucleases, amplification of DNA sequences using the polymerase chain reaction (PCR), detection of DNA and RNA using hybridization (Southern and Northern blotting), properties of cloning vectors and their use in constructing genomic and cDNA libraries, DNA sequencing and sequence analysis, creating and detecting mutations in DNA and introducing these mutations into a genome, and expression and characterization of proteins.
Fall 2020 Schedule
2.0 Credit Hours, Second Half Semester
Instructors: Greg Ducker & Matt Miller
MWF 8:35AM-9:25 AM
BC Students should register for Section 001, Class 17125
MBIOL 6420 - G3: Genetics, Genomes, and Gene Expression
This course covers transmission genetics, methods of genetic and genome analysis in model systems and humans, as well as transcriptional and post-transcriptional mechanisms of gene regulation. Lectures cover both classical achievements and recent advances in these fields, with readings based chiefly in the primary literature. Grades are based on exams and problem sets.
In previous years, we have found that some students have struggled in this graduate level course in Genetics. Success in G3 requires a foundational understanding of transmission genetics (i.e. successful completion of an undergraduate course in genetics) as the course focuses heavily on genetic analysis. All students should review the basic concepts and students who have not taken a comprehensive undergraduate course in Genetics or have been working in a lab for a number of years should delay taking G3 until the following fall and complete a prerequisite undergraduate course.
Fall 2020 Schedule
3.0 Credit Hours, Full Semester
Instructor: Anthea Letsou
MWF 8:35AM-9:25 AM
MB Students should register for Section 001, Class 4776
Non-program students should contact instructor and Bioscience PhD Office for a permission code to register for Section 002, Class 9193
BLCHM 6410 - Protein and Nucleic Acid Biochemistry
The Biochemistry course covers the structure and function of nucleic acids and proteins, as well as the thermodynamics and kinetics of their interactions with each other and with other biologically important molecules. It is expected that all students have taken an undergraduate course in Biochemistry, and you may find it useful to review chapters discussing the above-mentioned subjects in an undergraduate Biochemistry textbook. You will also need to have a basic working knowledge of kinetics and thermodynamics. (So, if you are not comfortable working with equilibrium constants, free energies, and rate constants, please review these topics in an undergraduate chemistry text.) There are no required texts for this class; readings from various texts will be made available to the class. Some professors may administer a pre-quiz at the start of their lectures to make sure you are adequately prepared for the material to be covered.
Cross-listed with MBIOL 6410
Fall 2020 Schedule
2.0 Credit Hours, First Half Semester
Instructors: Paul Sigala and Brenda Bass
MWF 10:45AM-11:35 AM
BC Students should register for Section 001, Class 1904
Non-program students should contact instructor and Bioscience PhD Office for a permission code to register for Section 002, Class 9192
MBIOL 6410 - Protein and Nucleic Acid Biochemistry
The Biochemistry course covers the structure and function of nucleic acids and proteins, as well as the thermodynamics and kinetics of their interactions with each other and with other biologically important molecules. It is expected that all students have taken an undergraduate course in Biochemistry, and you may find it useful to review chapters discussing the above-mentioned subjects in an undergraduate Biochemistry textbook. You will also need to have a basic working knowledge of kinetics and thermodynamics. (So, if you are not comfortable working with equilibrium constants, free energies, and rate constants, please review these topics in an undergraduate chemistry text.) There are no required texts for this class; readings from various texts will be made available to the class. Some professors may administer a pre-quiz at the start of their lectures to make sure you are adequately prepared for the material to be covered.
Cross-listed with BLCHM 6410
Fall 2020 Schedule
2.0 Credit Hours, First Half Semester
Instructors: Paul Sigala and Brenda Bass
MWF 10:45AM-11:35 AM
MB Students should register for Section 001, Class 4775
Non-program students should contact instructor and Bioscience PhD Office for a permission code to register for Section 002, Class 9191
BLCHM 6450 - Biophysical Chemistry
Topics covered include: Basics of thermodynamics and statistical mechanics, with applications in biochemistry; transport phenomena; enzyme kinetics and inhibition; kinetic isotope effects; principles and applications of absorbance, fluorescence, and CD spectroscopies.
Cross-listed with CHEM 5440, & CHEM 7450
Fall 2020 Schedule
2.0 Credit Hours, Second Half Semester
Instructor: Jessica M Swanson-Voth
MWF 9:35AM-10:40AM
BC Students should register for Section 001, Class 1905
Non-program students should contact instructor for instructions and permission code to register for cross listed Chemistry Department Section
MBIOL 6480 - Cell Biology
This course covers basic and advanced topics related to cell structure and function including cytoskeleton, membrane trafficking, protein targeting/modification and degradation, cell cycle regulation, and signal transduction.
Fall 2020 Schedule
1.5 Credit Hours, Second Half Semester
Instructors: Adam Hughes and Minna Roh-Johnson
MWF 10:15AM-11:35AM
MB Students should register for Section 001, Class 11438
Non-program students should contact instructor and Bioscience PhD Office for a permission code to register for Section 002, Class 11627
BLCHM 6460 - Protein Chemistry
This is a one half semester course which focuses on the mechanisms of chemical reactions involving peptides and proteins and methods for their study. Subject matter includes enzyme mechanisms, chemical modification of proteins and cofactor chemistry. Prerequisite: organic chemistry.
Cross-listed with CHEM 5460 & CHEM 7460
Fall 2020 Schedule
2.0 Credit Hours, First Half Semester
Instructor: Vahe Bandarian
MWF 8:20AM-9:25AM
BC Students should register for Section 001, Class 7642
Non-program students should contact instructor for instructions and permission code to register for cross listed Chemistry Department Section
BLCHM 7960 - Research
Laboratory rotations for students in the Graduate Programs Biological Chemistry.
A signed Rotation Verification Form and an e-mailed copy of the rotation report must be submitted to the Program Office in order to receive credit.
Rotation Schedule for 2020-21
(Please note: these dates do not correlate with the academic quarters.)
Fall 2020 Semester
1st Rotation: Monday, August 31 - Tuesday, October 13, 2020
2nd Rotation: Wednesday, October 14 - Wednesday, November 25, 2020
Spring 2021 Semester
3rd Rotation: Monday, January 11 - Friday, March 5, 2021
Lab Commitments can begin: Monday, March 8, 2021
MBIOL 7960 - Research
Laboratory rotations for students in Molecular Biology.
A signed Rotation Verification Form and an e-mailed copy of the rotation report must be submitted to the Program Office in order to receive credit.
Rotation Schedule for 2020-21
(Please note: these dates do not correlate with the academic quarters.)
Fall 2020 Semester
1st Rotation: Monday, August 31 - Tuesday, October 13, 2020
2nd Rotation: Wednesday, October 14 - Wednesday, November 25, 2020
Spring 2021 Semester
3rd Rotation: Monday, January 11 - Friday, March 5, 2021
Lab Commitments can begin: Monday, March 8, 2021
MBIOL 7570 - Case Studies and Research Ethics
An examination of research integrity and other ethical issues involved in scientific research. Topics may include scientific fraud, conflicts of interest, plagiarism and authorship designation, and the role of science in formulating social policy. This course is designed for graduate students, post-docs and regular faculty in the sciences.
Fall 2020 Schedule
1.0 Credit Hour, Sept 16 - Nov 11
Instructor: Joyce Havstad
W 4:00PM-5:30 PM, Online
Students should register for Section 001, Class 6514
Spring Semester
University Spring 2021 Class Schedule
Biological Chemistry Program
BLCHM 6200 - Critical Thinking in Research
BLCHM 6300 - Guided Proposal Preparation
3 Electives
Molecular Biology Program
MBIOL 6200 - Critical Thinking in Research
MBIOL 6300 - Guided Proposal Preparation
2 Electives
2021 Spring Semester MB Grid.pdf
Electives
- Designed to help students gain proficiency in areas of interest
- These courses vary by year and semester
- Many are taught every other year
- Available to first year students and advanced graduate students in thesis departments
Graduate Electives Spring 2021.pdf|Graduate Electives Spring 2020.pdf|Graduate Electives Spring 2019.pdf
Frequent MB Electives Spring 2021
- Regulation of Metabolism
- Advanced Statistical Modeling for Biologist
- Structural Methods
- Nucleic Acid Chemistry
- Applied Computational Genomics
- Cellular Signaling
- Utilization of Animal Models in the Development of Clinical Research Projects
- Molecular Mechanisms of Cancer
- Molecular Virology
- Topics in Immunology
- Advanced Immunology
Additional Frequent Electives
Frequent BC Electives Spring - Not Available Spring 2021
Frequent MB Electives Spring - Not Available Spring 2021
MBIOL 6200 - Critical Thinking in Research
In order to teach the skills required to be a successful independent scientist this course will teach students critical thinking strategies for successful research. This will include how to digest and analyze papers and problem solve, both of which will review and apply material from core courses. The instructors will develop specific course content. Topics may include: How to read a paper (read at home, discuss in class); Survey of the core services; Problem solving with open-ended problems posed on real-life or made-up situations. A focused effort will be made to help students identify topics that they can develop into grants in the Spring term. Grading will be based on participation and individual work.
Cross-listed with BLCHM 6200
Spring 2021 Schedule
2.0 Credit Hours, First Half Semester
T & TH 3:00PM-5:00PM, HSEB TBA
Instructors: Nels Elde
MB Students should register for Section 001, Class 10645
BLCHM 6300 - Guided Proposal Preparation
To prepare students for their thesis research, prelims, and qualifying exams, we will offer a guided proposal preparation course in the second half of the Spring semester that builds on their experience earlier in the semester (critical thinking in research, reading of primary literature and problem solving). The guided proposal writing course will provide an opportunity for students to create an original research proposal by critical review of other grants, training in hypothesis generation, scientific writing, and experimental design. The written original grant proposal will be used as a basis for an oral qualifying examination by a faculty committee.
Cross-listed with MBIOL 6300
Spring 2021 Schedule
2.0 Credit Hours, Second Half Semester
T & TH 3:00PM-5:00PM, HSEB TBA
Instructors: Clement Chow & Tim Formosa
BC Students should register for Section 001, Class 10648
MBIOL 6300 - Guided Proposal Preparation
To prepare students for their thesis research, prelims, and qualifying exams, we will offer a guided proposal preparation course in the second half of the Spring semester that builds on their experience earlier in the semester (critical thinking in research, reading of primary literature and problem solving). The guided proposal writing course will provide an opportunity for students to create an original research proposal by critical review of other grants, training in hypothesis generation, scientific writing, and experimental design. The written original grant proposal will be used as a basis for an oral qualifying examination by a faculty committee.
Cross-listed with BLCHM 6300
Spring 2021 Schedule
2.0 Credit Hours, Second Half Semester
T & TH 3:00PM-5:00PM, HSEB TBA
Instructors: Clement Chow & Tim Formosa
MB Students should register for Section 001, Class 10646
Oral Capstone
The written original grant proposal prepared in the Guided Grant Preparation course will be used as a basis for an oral capstone examination by a faculty committee. This exam will ensure that students meet our standards for thesis work and review material from the core courses before they join a department and lab. Students will prepare an R21-style grant proposal (~6 single-spaced pages, covering 2 years of work) to be submitted 5 days before the exam. They will present and defend the proposal in front of a 3-member capstone exam committee.
Capstone exams will be held during Final Exam Week:
Thursday, April 29 - Wednesday, May 5
BIO C 6600 - Regulation of Metabolism
Frequent BC Elective (Biochemistry Research Track)
Frequent MB Elective
This half-semester course will begin with a review of carbohydrate and lipid metabolic pathways, with an emphasis on an integrated understanding the pathways and what is known about their regulation. The course will progress to an in-depth analysis of current research in specific areas of nutritional sensing and metabolic regulation.
Spring 2021 Schedule
1.5 Credit Hours, Second Half Semester
Instructor: Janet Lindsley
T, Th 9:30AM - 11:00AM, TBA, Class 3476
(note: starts 10 min earlier than usual class times)
BIOL 6500 - Advanced Statistical Modeling for Biologist
Frequent MB Elective
This course is designed for life science graduate students with a perhaps rusty background in mathematics and statistics who wish to become real practitioners of the art of modern statistics. The course is based on the R programming language.
Spring 2021 Schedule
3.0 Credit Hours, Full Semester
Instructor: Frederick Adler
M, W 1:25PM - 2:45PM, ASB 210, Class 14898
BLCHM 6430 - Structural Methods
Frequent BC Elective (Structural Biology / Biophysics Research Track)
Frequent MB Elective
This course provides an integrated approach to the applications of NMR and X-ray crystallography in structural biology. Topics covered include: basic NMR theory, and the application of 2D and 3D NMR methods for the determining protein and RNA structures; methods of macromolecular crystallization and crystal structure determination.
Spring 2021 Schedule
1.5 Credit Hours, First Half Semester
Instructor: Chris Hill
M, W, F 9:40AM - 10:30AM, Canvas, Class 16992
CHEM 7150 - Bioinorganic Chemistry
Frequent BC Elective
Meets with CHEM 5150. This course provides a broad overview of metal sites in biology and is intended for students at the interface of Chemistry, Biology, Biophysics, and related disciplines. It focuses on our current understanding of the role of metals in the structure and function of proteins and nucleic acids, metalloproteins as elaborated inorganic complexes, physical methods used to study metal sites with emphasis on the synergism between model complexes and biochemical studies, and applications in medicine. Three lectures, one discussion per week for 7.5 weeks.
Spring 2021 Schedule
2.0 Credit Hours, Second Half Semester
Instructor: Matt Kieber-Emmons
M, W, F 9:35AM - 10:40AM, Canvas, Class 14926
CHEM 7270 - Organic Spectroscopy I
BC Elective
Students should gain an understanding of NMR theory, experimental set-up and spectral interpretation/identification of organic molecules from 1D and 2D solution NMR spectra. Specifically:
- Fundamentals of organic structural determination
- Components of the NMR spectrometer, data acquisition and sample considerations
- Chemical shift theory and estimation of 1H and 13C chemical shift through empirical formulas
- J-coupling theory, magnetic equivalence and higher order spectra, and use of spin decoupling for signal enhancement
- NMR relaxation – theory of longitudinal (T1) and transverse (T2) relaxation, experimental measurements of T1 and T2 (inversion-recovery, spin-echo, CPMG), quadrapolar relaxation effects, use of relaxation properties in spectral assignment
- Nuclear Overhauser Effect (NOE) – theory and application
- Multinuclear NMR – spectral interpretation for direct detection of 15N, 19F, and 31P nuclei
- Advanced 1D NMR techniques – theory and spectral interpretation of INEPT, DEPT, TOCSY, NOESY/ROESY data
- 2D NMR techniques – theory and spectral interpretat
Spring 2021 Schedule
2.0 Credit Hours, First Half Semester
Instructor: Bethany Buck-Koehntop
M, W, F 11:00AM - 12:05PM, Canvas, Class 15631
CHEM 7470 - Nucleic Acid Chemistry
Frequent BC Elective (Biochemistry Research Track)
Frequent MB Elective
Prerequisite: 2 semesters undergraduate organic chemistry.
Three lectures, one discussion per week for 7.5 weeks. Topics include chemical synthesis of DNA and RNA, nucleoside and oligomer analogs, chemistry of DNA damage and repair, nucleic acid-targeted drugs and binding agents.
Spring 2021 Schedule
2.0 Credit Hours, Second Half Semester
Instructor: Ming Hammond
M, W, F, 8:20AM - 9:25AM, Canvas, Class 15826
HGEN 6060 - Applied Computational Genomics
Frequent BC Elective
Frequent MB Elective
Genome Science Program Core Requirement
Prerequisites: Complete "Learn the Command Line" from codeacademy.com
This course will provide a comprehensive introduction to fundamental concepts and experimental approaches in the analysis and interpretation of experimental genomics data. It will be structured as a series of lectures covering key concepts and analytical strategies. A diverse range of biological question enabled by modern DNA sequencing technologies will be explored including sequence alignment, the identification of genetic variation, structural variation, and ChIP-seq and RNA-seq analysis. Students will learn and apply the fundamental data formats and analysis strategies that underlie computational genomics research. The primary goal of the course is for students to be grounded in theory and have the ability to conduct independent genomic analyses.
Spring 2021 Schedule
2.0 Credit Hours, Full Semester
Instructor: Aaron Quinlan
T, Th, 9:10AM - 10:30AM, EIHG TBA, Class 15422
HGEN 6481 - Cellular Signaling
Frequent MB Elective
This course will examine the mechanisms of a variety of eukaryotic signal transduction pathways, and explore how these pathways affect the behavior of cells within developing and adult tissues. The material will include readings and discussion of the primary literature, and emphasize experimental techniques and analyses.
Spring 2021 Schedule
1.5 Credit Hours, First Half Semester
Instructor: Charles Murtaugh
M, W, F 10:45AM - 11:35AM, TBA, Class 5553
MD CH 7891 - The Chemical Biology of Pain: Opioids and Beyond
Frequent BC Elective (Chemical Biology / Medicinal Chemistry Track)
In this half-semester course, we will introduce key concepts in Chemical Biology with an emphasis on examples from the primary literature. Topics will include chemical and biological compound library development, chemical genetics and target identification, and strategies for the development of chemical probes and therapeutic compounds. Students will leave the class with a working knowledge of the field of Chemical Biology and its relationship to medicinal chemistry and drug development, the ability to analyze the primary literature and to design experiments to test key questions at the interface between chemistry and biology.
Spring 2021 Schedule
2.0 Credit Hours, First Half Semester
Instructor: Eric Schmidt
M, W, F 1:00PM - 2:00PM, TBA, Class 5470
MDCRC 6530 - Utilization of Animal Models in the Development of Clinical Research Projects
Med-2-Grad Core Course Requirement
Frequent MB Elective
It is now possible to precisely modify any DNA sequence within the genome of the mouse. This course emphasizes using mouse models to dissect the genetic basis of human disease. Deletion of genes using homologous recombination will be covered extensively as will other methods of gene inactivation (anti-sense constructs, inhibitory RNA, etc.). New experimental systems for modeling human disease in zebra fish and C. elegans will also be covered.
Spring 2021 Schedule
2.0 Credit Hours, Full Semester
Instructor: Anthea Letsou
W 1:00PM - 2:30PM, TBA, Class 12885
ONCSC 6500 - Molecular Mechanisms of Cancer
Frequent BC Elective
Frequent MB Elective
Prerequisites: Concurrent enrollment or equivalent 1st year Cell Biology, Molecular Biology and Genetics.
In alternating years, this course is focused on the current understanding of the molecular and cellular biology of cancer along with how this knowledge relates to the diagnosis, treatment and prevention of cancer. The complementary sister-course is focused on clinical cancer biology. It is designed for graduate students and post-doctoral fellows in basic science departments with an interest in modern principles and practice of oncology. It will cover general principles and new developments in cancer etiology, detection, diagnosis, treatment, and prevention. The course is organized around specific diseases, using advances in each area to highlight modern principles and practice of oncology.
Spring 2021 Schedule
1.5 Credit Hours, Second Half Semester
Instructor: Sean Tavtigian
M, W, F 3:00PM - 4:00PM, Class 2944
PATH 6410 - Molecular Virology
Frequent MB Elective
Basic knowledge of molecular biology is required. The molecular biology of virus lifestyle strategies, including cell entry, nucleic acid replication, gene expression, assembly of progeny virions, interaction with the host cell, and molecular epidemiology. The course will provide both a general introduction to the diversity of virus lifestyles and a detailed analysis of several of these strategies.
Spring 2021 Schedule
1.5 Credit Hours, First Half Semester
Instructor: Vicente Planelles
M, W 1:00PM - 2:30PM, Canvas, Class 16804
PATH 7320 - Topics in Immunology
Frequent MB Elective
This course will address core topics in immunology including cellular and molecular mechanisms of innate and adaptive immune responses to infection, vaccines, autoimmunity and cancer immunology and immunotherapies.
Spring 2021 Schedule
1.5 Credit Hours, First Half Semester
Instructor: Scott Hale
T, TH 1:00PM - 2:30PM, Canvas, Class 15459
PATH 7360 - Advanced Immunology
Frequent MB Elective
Prerequisite: A survey course in Immunology (such as PATH 5030) and some exposure to Biochemistry, Cell Biology, and Genetics.
This is an advanced lecture and seminar course addressing topics of immunological research and interest. The course will focus upon original research articles, not a textbook. Students will be expected to participate in discussions. Class grade will be determined based upon classroom participation and a research proposal based upon some aspect of immunology covered in this course.
Spring 2021 Schedule
1.5 Credit Hours, First Half Semester
Instructor: Dean Tantin
T, TH 2:00PM - 3:30PM, Canvas, Class 16806
PHCEU 7011 - Fundamentals of Pharmacokinetics
Frequent BC Elective
Prerequisite: PHCEU 7010, or Special Permission from Instructor
This course will review fundamental aspects of pharmacokinetics with an emphasis on understanding concepts for compartmental and non-compartmental modeling, physiologic modeling, and modeling of targeted drug delivery systems. The goal of the course is to understand how these techniques can be used to optimize drug delivery.
Spring 2021 Schedule
3.0 Credit Hours, Full Semester
Instructor: James Herron & Shawn Owen
W, F 10:30AM - 12:00PM, Canvas, Class 11229
MD CH 7891 - Medicinal and Biological Chemistry
Frequent BC Elective (Chemical Biology / Medicinal Chemistry Track)
In this half semester course, we will begin by describing the physiology of pain and the current pain treatments. Subsequently, we will discuss the latest advances in understanding the mechanisms underlying various types of pain and the development of new investigational compounds for pain. We will seek an understanding of how drugs are discovered, developed, and approved using pain as an example.
Not Offered Spring 2021
2.0 Credit Hours
Instructor: Eric Schmidt
M, W, F 1:00PM - 2:00PM, HSEB 4100C
BIO C 6420 - Advanced Biochemistry
Frequent BC Elective (Biochemistry Research Track)
Frequent MB Elective
This course will focus on biochemical and biophysical approaches to studying proteins and their functional interactions. Topics covered will include: protein-ligand interactions, cooperativity and allostery, protein folding and design, spectroscopic techniques, analytical ultracentrifugation, calorimetry, biosensors, proteomics approaches, and protein structure prediction.
Not Offered Spring 2021
1.5 Credit Hours, First Half Semester
Instructors: Michael Kay and Wes Sundquist
T, TH 9:40AM - 11:00PM, HSEB 2908
HGEN 6421 - Genetics of Complex Diseases
Frequent MB Elective
Course work addresses issues relevant to the identification of genes underlying susceptibility to complex disorders. Subjects covered include advantages and disadvantages of isolates versus large population, utilization of affected sibling pairs, discordant sibling pairs and extended families. Methods taught include traditional case-control association methods and family based methods. Other subjects include locus and allelic heterogeneity, phenotypic heterogeneity, gene-gene and gene-environment interactions and density of polymorphic markers.
Not Offered Spring 2021
1.5 Credit Hours, First Half Semester
Instructor: Lynn Jorde
W 1:30PM - 3:30PM, HSEB 2969
PATH 7310 - Host Pathogen Interactions and Human Disease
Frequent MB Elective
This course will examine the mechanisms and consequences of microbial interactions with host cells and tissues. The means by which microbial pathogens stimulate and overcome host defenses and cause disease will be explored. This half- semester course is suitable for all graduate students.
Not Offered Spring 2021
1.5 Credit Hours, First Half Semester
Instructors: Jessica Brown & Matthew Mulvey
M, W, F 2:00-3:00, HSEB 5100B
HGEN 6020 - New Tools Of Genetic Analysis
Frequent MB Elective
Genetics meets Genomics
Have you felt like genetic analyses in recent papers are going over your head? Have you wondered what the current buzzwords like network and systems biology have to do with genetics? While transmission genetics continues to be a backbone of biological analysis, the development of multiple new genomic tools is adding considerably to the power of genetic analysis. In this class we will explore the new genetic tools through in-depth discussion of research papers and learn how these methods are being integrated into classical genetics of both established and emerging genetic systems. Among the topics to be discussed are: gene network analysis; systematic suppressor and enhancer screens; challenges to predicting the consequences of sequence variants; use of comparative sequence analyses as the basis of functional hypotheses; methods in gene identification; and using genetics in a systems level analysis of biological processes in the investigation of natural variation.
PREREQUISITES: Open to doctoral graduate students. Maximum enrollment is twelve (12) students.
CONTACT: Mark Metzstein (markm@genetics.utah.edu)
Not Offered Spring 2021
1.0 Credit Hours, Second Half Semester
Instructors: Mark Metzstein & David Grunwald
W 2:00-3:30, HSEB 4100D
ONCSC 6520-001 - Physiology & Medicine for the Molecular Biologist
Med-2-Grad Core Course Requirement
Frequent MB Elective
The goal of this course is to provide graduate students in the basic sciences with a richer understanding of human physiology and pathophysiology. This information is critical for understanding the importance of any molecular mechanism at the level of cells, organs and whole animals, and applying this information to humans.
This course is aimed for students interested in:
- Gaining an understanding on the broad implications of their research and basic science.
- Learning how their focus in molecular mechanisms translates to medical interventions.
- Obtaining a foundation in anatomy and physiology necessary that is critical for understanding how to characterize genetic engineered animal models
- Preparing themselves scientifically for careers in biotech or pharma industry.
We will teach the anatomy, physiology and pathophysiology relevant to a given organ system (heart, lung, kidney etc.). The relationship between molecular mechanism, pathophysiology and medicine will be emphasized. Each sections will be organized into three-1 hour lectures. Lectures will include up to date molecular details of interest and relevance to this audience. Though the course will utilize a textbook, McCance and Huether Pathophysiology, class participation is key as we will synthesize information to develop therapeutic strategies of today and tomorrow.
Not Offered Spring 2021
HGEN 6091 - Evolution & Development
Frequent MB Elective
This course will explore the molecular, developmental, and genetic mechanisms underlying evolutionary change, with an emphasis on current research in animal biology. Topics include regulatory networks and signaling pathways, modularity, developmental constraints, origin of animals, molecular/developmental origin of diverse body plans and appendages, and genetics of speciation. The class will consist of both lectures and discussions of current literature. Suitable for graduate students at all levels.
Not Offered Spring 2021
Spring 2018 Schedule
1.5 Credit Hours, Second Half Semester
Instructor: Gabrielle Kardon
T, Th 1:15-2:45, HSEB 2938
ADDITIONAL CERTIFICATES AND PROGRAMS
- There are several certificate programs graduate students can complete during their training in addition to the Ph.D.
- Students are encouraged to consider these programs when selecting electives
- Additional information can be found in Affiliated Research Programs and the Graduate School Degree Requirements page
GENOME SCIENCES PROGRAM
Genome Sciences Program Certificate
The goal of the Genome Sciences (GS) Program is to train the next generation of investigators to integrate genomics with biological and clinical research. Genome sciences merges functional genomics and translational biology to investigate biological systems at all levels of complexity.
MED-INTO-GRAD PROGRAM
Med-into-Grad activities and mentoring are integrated seamlessly with department-based requirements in order to provide comprehensive medical science education that will assist pre-doctoral students at each step of their graduate work, from classroom studies and thesis research, to developing long-term lines of investigation with an eye to translation and relevance to human disease.
Students should be a current PhD graduate student in the Colleges of Science, Medicine, Pharmacy, or Engineering, or the School of Medicine. They must have completed their first year of graduate school, have identified their thesis mentor, and have a strong interest in pursuing translational research during and following graduate school.
Utah Center for Clinical and Translational Science (CCTS)
Ruben Rocha, ruben.rocha@hsc.utah.edu