Assistant Professor of Microbiology and Immunology
Tumor Immunology, Tumor Heterogeneity, T cells, Tumor Evolution
The Reeves Lab studies tumor heterogeneity and its impact on the anti-tumor immune response, and how tumors evolve in response to immunotherapy
- Tanaka M, Lum L, … Reeves, MQ. Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma. Bioxriv. doi: 10.1101/2023.04.25.538140 (2023). PMCID: PMC10168251
- Dodagatta-Marri E, Meyer DS, Reeves MQ, et al. α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas. J. Immunother. Cancer 7, 1-15 (2019).
- Reeves MQ, Kandyba E, Harris S, et al. Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis. Nat. Cell Bio. 20, 699-709 (2018). (PMID: 29802408)
- McCreery (Reeves) MQ, Halliwill KD, Chin D, et al. Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers. Nat. Med. 21, 1514–20 (2015). (PMID: 26523969 / PMCID: PMC5094808)