Genome Engineering Research Emphasis Area
This Research Emphasis builds on the long history of genome engineering at Utah. It brings together researchers across many departments who are interested in one or more of the following aspects of genome engineering:
- Tools. To develop new methods of genome engineering.
- Disease. To manipulate genomes to create models of inherited disorders, or to test potential treatments of disease.
- Synthetic biology. To modify genomes for the creation of new biochemical pathways in organisms, for the generation of natural compounds or new compounds that can accelerate pharmacology.
The University of Utah General Catalog
BIOL 6140 - Advanced Genetics
Advanced Genetics covers the fundamentals of classical genetics and genetic analysis in prokaryotes and eukaryotes. Classical genetics encompasses the mechanisms of inheritance and the behavior of genes and chromosomes in somatic cells and germ cells. Genetic analysis is a branch of biological investigation that uses mutations and mutant phenotypes to study the function and behavior of cells and groups of cells, in isolation and in a developmental context. Prokaryotes and eukaryotes have different modes of inheritance and significant differences in gene regulation and in their cellular biology. Prokaryotes provided the foundational discoveries of molecular biology and continue to be a source of new genetic tools and biological understanding with health and ecological relevance. Modern eukaryotic genetics blends the tools of molecular biology, cell biology and classical genetics to investigate gene and cell function in complex organisms.
Bioscience Faculty
Cell Signaling, Genetics, Development, Inter-organ Communication, Drosophila, CRISPR, Plasma Proteomics
Structural Biology, Biochemistry, DNA repair, Eye Health
Drosophila Models of Human Disease, Microcephaly, Mechanisms of Virus-Induced Disease, Neuronal Stem Cells, Neurodevelopment
Nucleic Acids, Gene Editing, Biotechnologies, Single-molecule Biophysics, Cell Dynamics, Immunity
Zebrafish, Phenotypic Screening, Behavior, Neuropharmacology, Disease Models, Genome Editing, Therapeutics
Epitranscriptomics, RNA Modifications, RNA Editing, Pseudouridine, Inosine, Protein Evolution, Biomedicine, RNA Therapeutics
